Doktor Sleepless is a monthly comic book series written by Warren Ellis with art by Ivan Rodriguez that is published by Avatar Press, launched in July 2007. The comic draws from a wide range of ideas – from futurism and transhumanism to corporatism and counter-culture.

According to series writer Warren Ellis, Doktor Sleepless may be a man named John Reinhardt, a trust-fund baby and boy genius who is shunned by the counter-culture he helped found. After disappearing from the city of Heavenside three years ago, he suddenly returns having undergone some changes during the interim. Upon his return, he's transformed himself from a relatively mundane man into what he describes as a "cartoon mad scientist," calling himself "Doktor Sleepless."

Ellis compares the series to his earlier fan-favorite work on Transmetropolitan, published under the DC Comics imprint, Vertigo.

Due to a series of computer difficulties the series (along with other titles Ellis worked on at the time) was placed on hiatus. Release of new material was planned for early 2012 (after which the book would go on another hiatus), delayed several times and ultimately failed to materialize.